A PET or SPECT scan can map the brain by measuring the distribution and density of neurotransmitter receptors in certain areas. An fMRI scan, for example, can track changes that take place when a region of the brain responds during various tasks. Increasingly sophisticated forms of brain imaging - such as positron emission tomography (PET), single-photon emission computed tomography (SPECT), and functional magnetic resonance imaging (fMRI) - permit a much closer look at the working brain than was possible in the past. Researchers believe that - more important than levels of specific brain chemicals - nerve cell connections, nerve cell growth, and the functioning of nerve circuits have a major impact on depression. Certain areas of the brain help regulate mood. Science, though, tracks the seat of your emotions to the brain. Popular lore has it that emotions reside in the heart. This article will address the how different parts of the brain affect mood. Major advances in the biology of depression include finding links between specific parts of the brain and depression effects, discovering how chemicals called neurotransmitters make communication between brains cells possible, and learning the impact of genetics and lifestyle events on risk and symptoms of depression. Scientists have learned much about the biology of depression, but their understanding of the biology of depression is far from complete.
With this level of complexity, you can see how two people might have similar symptoms of depression, but the problem on the inside, and therefore what treatments will work best, may be entirely different. There are millions, even billions, of chemical reactions that make up the dynamic system that is responsible for your mood, perceptions, and how you experience life. Rather, many chemicals are involved, working both inside and outside nerve cells. To be sure, chemicals are involved in this process, but it is not a simple matter of one chemical being too low and another too high.
It's believed that several of these forces interact to bring on depression. Rather, there are many possible causes of depression, including faulty mood regulation by the brain, genetic vulnerability, and stressful life events. Research suggests that depression doesn't spring from simply having too much or too little of certain brain chemicals. It's often said that depression results from a chemical imbalance, but that figure of speech doesn't capture how complex the disease is. Onset of depression more complex than a brain chemical imbalance
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